住院患者鲍曼不动杆菌院内感染的分布及防治措施

Distribution and Preventive Measures of Nosocomial Infection of Acinetobacter Bauman in Hospital

目的:通过回顾性分析住院患者发生院内感染的病原体的分布特征和耐药性,探讨院内感染的防控措施。方法:收集我院6年来发生院内感染患者感染标本,选择阳性菌株648株,分析标本来源、细菌谱和耐药性。结果:住院患者发生下呼吸道感染和伤口创面感染率较高,与其他部位感染率比较差异显著(P<0.01);所感染的细菌以鲍曼不动杆菌和金黄色葡萄球菌较多见,与其他感染的细菌种类比较,存在显著性差异(P<0.01,P<0.05);所感染的鲍曼不动杆菌对亚胺培南和头孢哌酮/舒巴坦比较敏感,但伴随用药时间的持续,耐药率呈上升趋势。结论:住院患者发生院内感染以鲍曼不动杆菌感染率较高,随用药时间延长,用药种类增多,其耐药比率也越来越高,为了早预防和正确诊治,需要积极采取措施。

Objective: To analyze the distribution characteristics and drug resistance of pathogens causing nosocomial infection in hospitalized patients,and to explore the prevention and control measures of nosocomial infection. Methods: 648 cases of nosocomial infection were collected in our hospital during the past 6 years,and the positive strains were selected. The sources,bacterial spectrum and drug resistance of the specimens were analyzed. Results: The incidence of lower respiratory tract infection and wound infection in hospitalized patients was higher,and there was significant difference compared with other sites( P <0.01); The infection of Bauman and Staphylococcus aureus was more common,and compared with other bacteria species,there were significant differences( P <0.01,P <0.05); The infection of Acinetobacter baumannii was sensitive to imipenem and Cefoperazone/sulbactam,but the drug resistance rate was on the rise with the duration of administration of Bauman. Conclusion: Bauman Acinetobacter infection rate is higher in hospitalized patients.With the extension of the drug and the increase in the types of drugs,The rate of drug resistance is more and more high. In order to prevent and correct diagnose and treat,positive measures should be take.