PDW、PLT、MPV及BISAP评分对急性胰腺炎病情程度的预测价值

The predictive value of PDW, PLT, MPV and the BISAP grade for the acute pancreatitis disease

目的考察血小板分布密度(PDW)、血小板(PLT)、平均血小板体积(MPV)及急性胰腺炎严重程度床边指数(BISAP)评分对急性胰腺炎(AP)病情程度的预测价值。方法选取2012年1月至2016年9月本院诊治的急性胰腺炎(AP)患者121例作为研究对象,根据AP的病情严重程度分为轻症急性胰腺炎(MAP)组(n=67)和重症急性胰腺炎(SAP)组(n=54)。比较两组患者各指标的差异,并应用Logistic回归模型和ROC曲线分析PDW、PLT、MPV和BISAP评分对AP的预测价值。结果与MAP组相比,SAP组的PDW、MPV和BISAP评分均显著提高,而PLT显著降低,差异具有统计学意义(P<0.05)。Logistic回归模型和ROC曲线结果显示PDW、PLT、MPV和BISAP评分是急性胰腺炎病情程度的独立因素和预测因子(P<0.05)。结论 PDW、PLT、MPV及BISAP评分可作为急性胰腺炎病情严重程度的评价指标之一。

Objective To investigate the predictive value of platelet distribution width（PDW）,platelet（PLT）,mean platelet volume（MPV） and the bedside index for severity in acute pancreatitis（BISAP） grade for the acute pancreatitis （AP）disease. Methods 121 cases of acute pancreatitis patients were collected from January 2012 to September 2016 in our hospital as research objects. According to the severty of illness ,patients were divided into mild acute pancreatitis （MAP）group,67 cases,and severe acute pancreatitis（SAP）group,54 cases. Logistic regression model and ROC curve were used for the evaluation of the predictive value. Results Compared with the MAP group,the PDW,MPV and BISAP grade were significantly increased in SAP group ,but the PLT was significantly decreased ,the difference was statistically significant（P〈0.05）. Logistic regression model and ROC curve results showed that the PDW,PLT,MPV and BISAP grade were the independent factors and predictive factors of the AP disease （P〈0.05）. Conclusion PDW,PLT,MPV and BISAP grade could be used as the evaluation indicator for the AP disease severity.