联合综合心理干预对复发性抑郁症患者抑郁情绪、生命健康质量及神经递质的影响

Influence of comprehensive psychological intervention on depressive mood,life health quality and neurotransmitter in patients with recurrent depression

目的探讨联合综合心理干预对复发性抑郁症患者抑郁情绪、生命健康质量及神经递质的影响。方法收集2014年4月~2015年6月在江苏省淮安市第三人民医院进行住院治疗的复发性抑郁症患者80例,按照随机数字表法分为对照组(40例)、观察组(40例)。对照组患者接受常规干预,观察组患者接受常规干预联合综合心理干预。比较两组患者抑郁情绪评分、生命健康质量评分及血清单胺类神经递质含量。结果干预前,两组抑郁情绪、生命健康质量评分,血清中单胺类神经递质含量差异无统计学意义(P>0.05)。干预后,观察组抑郁情绪评分低于对照组,生命健康质量评分高于对照组,观察组患者血清中去甲肾上腺素、五羟色胺、多巴胺的含量高于对照组患者(P<0.05)。结论综合心理干预可缓解复发性抑郁症患者的抑郁情绪,提升生命质量。

Objective To study the influence of comprehensive psychological intervention on depressive mood, life health quality and neurotransmitter in patients with recurrent depression. Methods From April 2014 to June 2015, 80 patients with recurrent depression in the Third People＇s Hospital of Huai＇an City were divided into control group （40 cases） and observation group （40 cases） by random number table. Patients in the control group were treated with routine clinical intervention, while those in observation group were treated with comprehensive psychological intervention combined with routine clinical intervention. The scores of depressive and life quality and the serum content of monoamine neurotransmitter in the two groups were compared. Results Before the intervention, there were no significant differences in the scores of depressive and life quality and the serum content of monoamine neurotransmitter be tween the two groups （P 〉 0.05）. After intervention, the scores of depressive in the observation group were lower than those in the control group, the Scores of life quality in the observation group were higher than those in control group, the levels of NE, 5-HT, DA in the observation group were higher than those in control group （P 〈 0.05）. Conclusion Comprehen sive psychological intervention can relieve depression and improve the quality of life in patients with recurrent depression.