针刺调控炎性反应在抗缺血再灌注损伤中的研究进展

Research on Acupuncture in Regulating the Inflammatory Reaction in Anti-ischemia-reperfusion Injury

缺血再灌注过程中诱发的炎性反应是造成脏器继发性损伤的主要因素之一,如何缓解缺血再灌注时的炎性反应已成为研究的热点。目前研究表明,针刺不但可以直接抑制炎性细胞浸润及调控炎性相关细胞因子的表达,还能调控炎性信号传导通路,抑制炎性反应,从而有效改善缺血再灌注损伤。现就目前针刺调控炎性反应拮抗脏器缺血再灌注损伤的效应机制进行综述。

The inflammatory response during ischemia-reperfusion is one of principal reasons for secondary organ injury. Therefore, the inhibition of inflammation has become a research hot spot. The current research showed that acupuncture can not only directly inhibit the infiltration of inflammatory cells and regulate the expression of inflammatory cytokines, but is also involved in the overall regulation of the inflammatory signaling pathway and inhibition of the inflammatory response, thereby effectively improving ischemia-reperfusion injury. Here, we review research on the mechanism of acupuncture in ischemia-reperfusion injury via regulation of the inflammatory response.