支架辅助弹簧圈栓塞治疗颅内宽颈动脉瘤的临床研究

Clinical Study on Stent-Assisted Coil Embolization for the Treatment of Intracranial Wide-Necked Aneurysm

目的对比单纯弹簧圈栓塞与支架辅助弹簧圈栓塞介入治疗颅内宽颈动脉瘤的临床疗效。方法选取我院2014年7月至2016年6月收治的50例颅内宽颈动脉瘤患者作为研究对象,随机分为两组各25例。对照组患者采用单纯弹簧圈栓塞介入治疗,治疗组患者采用支架辅助弹簧圈栓塞介入治疗,比较两组的临床疗效、术后一年复发率,以及手术前后的相关评分指标。结果治疗组的治疗总有效率为96.0%,显著高于对照组的72.0%(P<0.05);治疗组的术后1年复发率为0.0%,显著低于对照组的16.0%(P<0.05)。术前,两组患者的GCS评分、MRS评分和BI评分比较,差异无统计学意义(P>0.05);术后,治疗组的GCS评分、MRS评分和BI评分均显著优于对照组,差异有统计学意义(P<0.05)。结论支架辅助弹簧圈栓塞介入治疗颅内宽颈动脉瘤效果显著,具有较高的临床应用价值。

Objective To compare the clinical curative effects of simple coil embolization and stent-assisted coil embolization for the treatment of intracranial wide-necked aneurysm. Methods 50 cases of patients with intracranial wide-necked aneurysm admitted to our hospital from July 2014 to June 2016 were selected as research objects, and randomly divided into two groups, with 25 cases in each group. The control group received simple coil embolization, while the treatment group received stent-assisted coil embolization. The clinical effect, 1-year postoperative recurrence rate, and related rating indicators before and after surgery were compared between two groups. Results The total effective rate of treatment of treatment group was 96.0%, significantly higher than 72.0% of control group （P 〈0.05）. The 1-year postoperative recurrence rate of treatment group was 0.0%, significantly lower than 16.0% of control group （P 〈0.05）. Before surgery, no statistical difference was found between two groups in the GCS score, MRS score or BI score （P 〉0.05）; After surgery, the GCS score, MRS score and BI score of treatment group were significantly better than those of control group （all P 〈0.05）. Conclusions Stent-assisted coil embolization has significant effect for the treatment of intracranial wide-necked aneurysm, which shows high application value in clinic.