缺血性脑卒中静脉溶栓后出血转化相关因素的研究进展

Research progress of hemorrhagic transformation after intravenous thrombolysis in ischemic stroke

在我国人口老龄化日益加速的情况下,脑卒中对我国人口的危害也日益突出,其具有高发病率、高复发率、高致残率、高致死率、经济负担重的特点,已成为我国人口第一位死亡原因。随着缺血性脑卒中静脉溶栓研究的大量进行,出血性转化的危险因素及预测指标等引起了很大关注。本文对急性缺血性卒中静脉溶栓治疗后出血性转化的危险因素及相关预测指标进行综述,通过分析不同的临床危险因素及预测指标的应用价值,以期为临床医师对急性缺血性脑卒中患者是否行静脉溶栓进行快速决策以及为溶栓后脑出血风险的预测提供依据。

With the increasing population aging in our country,stroke harm to our national have become increasingly prominent,which has the characteristics of high incidence rate,high recurrence rate,high disability rate,high mortality rate and economic burden,has become the first cause of death in our country.With the development of intravenous thrombolysis in ischemic stroke,the risk factors and predictors of hemorrhagic transformation have attracted much at- tention.This paper reviewed the clinical risk factors and forecasting index of hemorrhagic transformation in acute is- chemic stroke after intravenous thrombolysis.The different clinical risk factors and application value of forecasting index were analyzed,in order to clinicians on whether patients with acute ischemic stroke for intravenous thrombolysis for rapid decision-making and provide for the prediction of the risk of intracerebral hemorrhage after thrombolysis.