热敏灸配合补肾强骨方治疗膝关节骨性关节炎的效果及对炎性因子的影响

Effect of thermal moxibustion combined with Bushen Qianggu Recipe in the treatment of knee osteoarthritis and the effect of inflammatory factors

目的分析对膝关节骨性关节炎患者(KOA)给予热敏灸、补肾强骨方联合治疗的效果及炎性因子的影响。方法选择2016年5月~2017年5月在我院收治的KOA患者100例进行观察,采用随机数字分组法将其分为对照组、联合组,每组50例。对照组单独运用补肾强骨方治疗,联合组采用热敏灸、补肾强骨方联合治疗。治疗3个月,观察两组治疗效果、膝关节功能(Lysholm)评分、疼痛视觉模拟(VAS)评分、治疗前后检测炎性因子(肿瘤坏死因子、白介素-1、超敏C反应蛋白)水平变化情况。结果经过3个月治疗后,联合组Lysholm评分、总有效率均显著高于对照组(P<0.05)。联合组肿瘤坏死因子、白介素-1水平、超敏C反应蛋白水平、VAS评分显著低于对照组,差异有统计学意义(P<0.05)。结论对KOA患者给予热敏灸、补肾强骨方联合治疗可以迅速改善患者的膝关节功能,抑制炎性反应,减轻患者疼痛感,疗效显著。

Objective To analyze the efficacy of thermal moxibustion combined with Bushen Qianggu Recipe in the treatment of knee osteoarthritis （KOA） and the effect of inflammatory factors.Methods One hundred patients with KOA in our hospital from May 2016 to May 2017 were observed,all the patients were divided into the combined group and the control group,with 50 cases in each group,by random number table method.The control group was treated with Bushen Qianggu recipe,the combined group was treated with hermal moxibustion and Bushen Qianggu Recipe.Treat- ment for 3 months,the clinical effects,Lysholm score,VAS score and the levels of inflammatory factors before and after treatment （tumor necrosis factor,interleukin-l,and hypersensitive C-reactive protein） were observed of the two groups. Results After？treatment for 3 months,the Lysholm score and the total effective rate of the combined group were higher than those of the control group（P〈0.05）.The levels of tumor necrosis factor, interleukin-l,hypersensitive C-reactive pro- tein and VAS score in the combined group were significantly lower than those in the control group, the difference was statistically significant （P〈0.05）.Conclusion The combination of thermal moxibustion and Bushen Qianggu recipe can improve the knee function , inhibit inflammatory reaction and relieve the pain of patients in KOA patients, and the clinical efficacy is remarkable.