负压引流治疗急性根尖周炎的疗效及其对患者炎症因子水平的影响

Efficacy of Vacuum Drainage for Acute Periapical Periodontitis and its Influence on Inflammatory Factors

目的探讨负压引流治疗急性根尖周炎的疗效及其对患者炎症因子水平的影响。方法将120例急性根尖周炎患者(120颗患牙)随机分为对照组(60例)与观察组(60例),对照组采用常规开髓引流术治疗,观察组接受常规开髓以及负压引流术治疗。结果观察组治疗有效率高于对照组,差异有统计学意义(P<0.01)。治疗前,两组患者咬合VAS评分、静息VAS评分,根管渗出液C反应蛋白(CRP)、前列腺素E2(PGE2)相比差异无统计学意义(P>0.05);治疗后,观察组根管咬合VAS评分、静息VAS评分,根管渗出液CRP、PGE2均低于对照组,差异有统计学意义(P<0.01)。结论负压引流治疗急性根尖周炎的疗效良好,具有术后痛感轻、炎症反应轻等优点。

Objective To investigate the efficacy of vacuum drainage for acute periapical periodontitis and its influence on inflammatory factors. Methods 120 cases of acute periapical periodontitis（120 teeth） were divided into a control group（60 cases） and an observation group（60 cases） randomly, and control group was given routine open-dental-pulp drainage, while observation group received routine open-dental-pulp vacuum drainage. Results The response rate of observation group was obviously higher than that of control group （P 〈 0.01）. Before treatment, no obvious differences were found in the occlusal and＇ resting VAS scores, root canal exudate C-reactive protein （CRP） and prostaglandin E2 （PGE2） between the 2 groups （P 〉 0.05）, After treatment, these before-mentioned indexes of observation group were obviously lower than those of con＇trol group （P 〈 0.01 ）. Conclusion The vacuum drainage for acute periapical periodontitis shows good efficacy, which can relieve postoperative pain and inflammatory reaction.