康复新液在预防宫颈冷刀锥切术后感染及出血的临床研究

Clinical study on effect of Kangfuxin Fluid on preventing infection and hemorrhage after cold knife conization

目的探讨宫颈上皮内瘤样病变Ⅲ级(CINⅢ)患者行宫颈冷刀锥切(CKC)术后局部浸润康复新液预防术后感染及出血的作用。方法选取2015年1月至2016年12月因CINⅢ在该院行CKC术患者80例,分为观察组和对照组(各40例),观察组行CKC术后局部浸润康复新液纱布压迫止血,对照组术后局部浸润聚维酮碘纱布压迫止血,观察两组术后近期并发症(发热感染率、阴道流血时间及宫颈创面愈合时间)和远期并发症(宫颈粘连/狭窄、晚期出血)情况并进行比较。结果观察组术后发热感染率、阴道流血时间、创面愈合时间及宫颈粘连发生率均低于对照组,差异均有统计学意义(P<0.05);两组晚期出血发生率比较,差异无统计学意义(P>0.05)。结论康复新液可以有效预防CKC术后创面感染等并发症,具有临床应用价值。

Objective To explore the effect of Kangfuxin Fluid by local infiltration for preventing the postoperative infection and hemorrhage after after cold knife eonization （CKC） in the patients with grade Ⅲ cervical intraepithelial neoplasia （CIN）. Meth- ods Eighty cases of grade Ⅲ CIN treated by CKC in this hospital from January 2015 to December 2016 were selected and randomly divided into the control group and observation group, 40 cases in each group. The observation group conduct the Kangfuxin Fluid infiltrated gauze for compression hemostasis after CKC, while the control group used the povidone iodine infiltrated gauze for conducting compression hemostasis. The short term complications （fever infection rate, vagina] bleeding time and cervical wound healing time） and long term complications（cervical adhesion/narrow, late bleeding） were observed and compared between the two groups. Results The incidence of postoperative fever infection, vaginal bleeding time. wound healing time and rate of cervical adhesion in the observation group were lower than those in the control group, and the differences were statistically significant （P〈0.05） ; the late bleeding occurrence rate had no statistical difference between the two groups（P〉0. 05）. Conclusion Kangfu.xin Fluid can effectively prevent the complications such as wound infection after CKC, and has clinical application value.