氧化应激和自噬在动脉粥样硬化中的作用被引量：7

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摘要动脉粥样硬化（atherosclerosis,As）是一种多因素所致的慢性的、渐进性的动脉炎症性疾病,以动脉壁变硬增厚、弹性减退和管腔狭窄为主要病变特征。虽然AS的发病机制及病理演变尚未明晰,但是研究证实脂质代谢异常及氧化应激损伤是其主要原因之一。近年来研究发现,氧化应激能够诱导细胞发生自噬现象以减轻氧化损伤[1]。有学者在20世纪50年代首次提出了细胞自噬的概念。自噬,

作者李超姜枫李运伦

机构地区山东中医药大学山东中医药大学附属医院

出处《重庆医学》 CAS 北大核心 2017年第35期5020-5022,共3页 Chongqing medicine

基金国家自然科学基金资助项目(81473653)

关键词动脉粥样硬化氧化性应激自噬

分类号 R543.5 [医药卫生—心血管疾病]

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