糖尿病肾病患者肾功能检验指标临床意义探究

Discussion on clinical significance of renal function test index in patients with diabetic nephropathy

目的：对肾功能检验指标在糖尿病肾病患者中的意义进行探讨.方法：选取168例我院确诊的糖尿病患者作为观察组,其中84例患者不合并有肾脏病变,84例患者合并有肾脏病变;同时将我院40例进行常规体检的健康人群作为对照.检测所有受试对象肾功能检验指标,包括尿微量白蛋白（mAlb）、 血清肌酐（Cr）及尿素氮（BUN）的水平.结果：尿mAlb、 血Cr及BUN在合并有肾脏病变的糖尿病患者中的水平显著高于常规体检的健康人群和不合并有肾脏病变的糖尿病患者,差异有统计学意义（P〈0.05）.结论：肾功能检验指标mAlb、Cr及BUN在糖尿病肾病患者中的水平显著升高,可作为糖尿病合并肾脏病变的临床诊断指标.

Objective： This study aims to explore the significance of renal function indexes in patients with diabetic nephropathy. Methods： 168 patients with diabetes diagnosed in our hospital were enrolled as the observation group, including 84 patients with renal lesions and 84 patients without renal lesions. As comparison, 40 healthy subjects were collected as the control group. Renal function markers including urinary microalbumin （mAlb） , serum creatinine （Cr） and blood urea nitrogen （BUN） levels were detected. Results： The levels of urinary mAlb, Cr and BUN in diabetic patients with renal diseases were significantly higher than those in health controls and diabetic patients without renal diseases. The difference was statistically significant （P 〈 0.05） . Conclusion： Levels of mAlb, serum Cr and BUN in patients with diabetic nephropathy were significantly increased, which could be used as indicators of diabetes with kidney diseases.