摘要
中药具有很好的降糖作用,其降糖作用较温和,时间较持久,不良反应较少。近年来,中药降糖作用的研究开始从新靶蛋白和通路的机制着手进行,如通过激活腺苷酸活化蛋白激酶(AMPK)通路可实现降糖作用,黄芪多糖、姜黄素、黄连素、大黄素、苦瓜总皂苷、降糖消渴颗粒、益糖康方、降糖三黄片、健脾消渴方、糖耐康颗粒等中药单体或复方可通过这一途径发挥降糖作用。
Traditional Chinese medicine shows good hypoglycemic effect with mild efficacy, long duration and few adverse reactions. In recent years, the researches on the hypoglycemic effect of Ruikang Hospital Affilliated to traditional Chinese medicine mainly started from the mechanism of new target protein and pathway, for example, Chinese medicine monomers or compounds including astragalus polysaccharide, curcumin, berberine, emodin, total saponins of momordicacharantia, total saponins of momordicacharantia, Yitangkang, Jiangtang Sanhuang tablets, Jianpixiaokefang and Tangnaikang granule can activate Adenosine monophosphate (AMP) - activated protein kinase (AMPK) to play hypoglycemic effect.
出处
《中国药师》
CAS
2017年第12期2225-2228,共4页
China Pharmacist
关键词
中药
腺苷酸活化蛋白激酶信号通路
降糖作用
研究进展
Chinese medicine
Adenosine monophosphate (AMP) -activated protein kinase
Hypoglycemic effect
Research progress