黑色素纳米颗粒的特性与应用研究进展

Research progress on characteristics and applications of melanin nanoparticles

黑色素纳米颗粒除了具备黑色素固有的优良性质如金属离子螯合性、光热转换性等之外,还具有高分散稳定性以及良好的生物相容性和生物可降解性,且易于表面改性或负载功能性物质来增强性能,从而用于靶向特定部位和治疗疾病。本文对黑色素纳米颗粒的特性、制备及应用研究进行综述,旨在为进一步开发其应用提供参考,为生物、医学等领域的实践提供理论依据。

Melanin nanoparticles （MNPs） not only retain the inherent characteristics of melanin （metal ion chelation, photothermal conversion property, etc.）, but also can exhibit more excellent properties, such as high dispersion stability, good biocompatibility and biodegradability, etc. Furthermore, these performances can be enhanced to target the specific sites and treat diseases by the surface modification or combination with functional substance. In this paper, the characteristics, preparation methods and applications of MNPs were reviewed. It provides a reference for further develop- ment of application for MNPs, and theoretical basis for practice in biology, medicine and so on.