半乳糖凝聚素-3在心肌梗死后心室重构和心力衰竭中作用的研究进展

Research on role of galectin-3 in ventricular remodeling and heart failure after acute myocardial infarction

心力衰竭作为多种心血管疾病的共同归宿和主要死因,早期诊断和有效干预是提高患者预后结果和转归的重要手段。半乳糖凝聚素-3(Gal-3)是近年来出现的一种新的生物标志物,与心肌纤维化及心力衰竭相关,在心力衰竭的诊断及治疗中具有参考价值,可有望作为心力衰竭治疗的一个新靶点。

Heart failure is a common outcome of a variety of cardiovascular disease and the main cause of death,early diagnosis and effective intervention may improve the prognosis of patients. Galectin-3 has been found to be a new biomarker of myocardial fibrosis and heart failure in recent years. It plays a certain role in the diagnosis and treatment of heart failure.Galectin-3 plays a key role in ventricular remodeling and heart failure,which can be used as a new target in the treatment of heart failure.