摘要
近些年,随着PET/CT设备及心脏正电子示踪剂的快速发展,PET心肌血流灌注显像(PET-MPI)在临床上的作用逐渐加强.心肌血流灌注定量分析提供了心肌血流的客观评价标准,可以客观、准确地发现早期灌注异常,准确地对冠心病进行危险分层、预后评价和客观判断治疗效果,为冠心病临床诊治、心脏的生理和病理生理学领域的活体无创性研究提供重要信息.笔者就PET-MPI及其定量分析的研究进展进行综述.
With the improvement of positron emission computed tomography (PET/CT) devices and the availability of cardiac positron tracers, the clinical interest in myocardial perfusion PET(PET-MPI) has increased over the years. PET-MPI enables noninvasive and accurate quantification of myocardial blood flow(MBF) and myocardial flow reserve(MFR), making it possible to enhance detection of early stages of vascular dysfunction, improve risk stratification of coronary heart disease, guide clinical management, evaluate efficacy and prognosis. The aim of this narrative review was to summarize the progress of cardiac PET for myocardial perfusion and its quantitative analysis.
出处
《国际放射医学核医学杂志》
2017年第6期423-429,共7页
International Journal of Radiation Medicine and Nuclear Medicine
基金
天津市卫生和计划生育委员会科技基金重点攻关项目(16KG145)
天津市滨海新区卫生和计划生育委员会科技项目(2015BWKL002)