艾滋病病毒感染者的疫苗接种进展与展望

Review for progress of vaccination for patients with HIV infection

全球特别是我国艾滋病的流行形势依然严峻。艾滋病病毒(human immunodeficiency virus,HIV)感染者的疫苗接种预防策略国外相对完善,国内基本处于空白状态。本文对HIV感染者疫苗接种的接种人群、时机、疫苗种类、接种方式、剂量、程序以及应考虑接种的灭活疫苗和减毒活疫苗进行综述,并结合国外研究最新进展对进一步研究方向以及对我国的启示进行思考和展望。

The prevalence of acquired immune deficiency syndrome （AIDS） in the world especially in China is still high. While vaccination strategies for human immunodeficiency virus （HIV） infected people are well developed in de- veloped countries, it remains unknown in China. In this paper, vaccination strategies for HIV infected persons including physical conditions, vaccination times, vaccine types, administration methods, doses, schedules, and priority to vaccinate inactivated or attenuated live vaccines were reviewed. Together with the progress of new published researches, we provided some suggestions which may be benefit for further research in China.