298例接受抗病毒治疗艾滋病患者的心理健康状况及其影响因素分析

Analysis of mental health status and related factors in 298 AIDS patients receiving antiretroviral therapy

目的了解安徽省接受抗病毒治疗的艾滋病(acquired immunodeficiency syndrome,AIDS)患者的心理健康状况及其影响因素,为促进该人群的身心健康提供参考。方法采取定量调查的方式对2013年1月~2014年6月在安徽省3个城市中接受CD4^+T细胞检查的AIDS患者进行问卷调查,收集病人的一般人口学特征以及心理健康状况等信息进行分析。结果研究的参与者中,有63人(21.1%)存在焦虑状况;有126人(42.3%)存在抑郁状况。多因素Logistic回归分析中,AIDS患者有宗教信仰是焦虑状况发生的相关因素(OR=2.221,95%CI:1.094~4.509);患者具有依从性、婚姻状况为已婚或同居、文化程度为初中和大专及以上、所在地为淮北市、知晓抗病毒治疗需终生服药是抑郁状况发生的相关因素(均有P<0.05)。结论 3个城市AIDS患者焦虑和抑郁状况较为普遍且受多重因素的影响,因此增加患者的依从性、抗病毒治疗需终生服药的知晓情况等可能对于降低焦虑和抑郁情况的发生具有重要意义。

Objective To explore the mental health status and related factors of acquired immunodeficiency syn- drome （AIDS） individuals receiving antiviral therapy （ART） in Anhui Province, and to provide appropriate measures for improving their physical and mental health. Methods Quantitative questionnaire survey was conducted among AIDS pa- tients with positive CIM ~ T cell who have received treatment in 3 cities of Anhui Province to collect the general demographic characteristics and mental health status of patients from january 2013 to June 2014. Results 63 （21.1%） patients were equipped with anxiety syndrome and 126 （42. 3% ） with depression. Multivariate Logistic regression analysis showed that holding religious belief was related to anxiety （ OR =2. 221,95% CI：I. 094-4. 509） , good ART adherence, marital status was married or cohabitation, educational level was junior high school or college and above, area in Huaibei and knowing antiviral treatment was a lifelong process on medication were influencing factors of depression （ all P 〈 0.05 ）. Conclusions Anxiety and depression were common syndrome among AIDS patients in 3 cities of Anhui Province and were related to multiple factors. It was important to increase ART adherence and the awareness of lifelong medication to reduce anxiety and depression incidence.