氟保护漆对儿童第一恒磨牙龋病的预防效果评价

Evaluation of effects of fluoride varnish on prevention of first permanent molar caries

目的 :比较氟保护漆与氟化泡沫在预防第一恒磨牙窝沟龋的临床效果及学生接受程度,为儿童和青少年龋齿的预防提供新的干预措施。方法:随机抽取上海市杨浦区3所小学,6~8岁学生600例进行研究,将其随机分为试验A组(多乐氟氟保护漆组)200例800颗牙、试验B组(氟化泡沫组)200例800颗牙、C组(对照组)200例800颗牙,对A、B组学生第一恒磨牙分别应用2.26%多乐氟氟保护漆、1.23%氟化泡沫进行防龋治疗,C组为空白对照,每半年1次对3组学生进行健康教育,共持续2年(4次),于6、12、18、24个月分别计算各组的第一恒磨牙龋齿发生率。采用SPSS 10.0软件包对数据进行统计学分析。结果:6个月后,A、B、C 3组龋齿发生率相比无显著差异(P>0.05);12、18、24个月后,B组龋齿发生率显著高于A组(P<0.05),并且A、B试验组龋齿发生率均显著低于对照组(P<0.05)。结论:多乐氟氟保护漆与氟化泡沫均有良好的防龋效果,但多乐氟氟保护漆的防龋作用优于氟化泡沫,而且操作简单、安全、方便,经济成本更低。

PURPOSE： To compare fluoride varnish and fluoride foam＇s effectiveness of preventing first permanent molar caries, and discuss patients＇ acceptance of the 2 materials among pupil patients. METHODS： Six hundred pupils aged 6~8 years from 3 primary schools in Shanghai Yangpu District were randomly selected.The subjects were randomly divided into 3 groups, with 200 students having 800 teeth in each. Two of these groups were experimental groups that receive fluoride varnish （Group A） and fluoride foam （Group B） respectively, and the third group （group C） was control group.Pupils in group A and group B received 2.26% Toro fluoride fluoride varnish, 1.23% fluoride foam was applied to the first molars. In the next 2 years, all pupils received dental health education every half year. The pupils＇ conditions of first permanent molar caries were checked in the sixth, twelfth, eighteenth and twenty-fourth month since the study started. Statistical analysis was performed using SPSS 10.0 software package. RESULTS： After 6 months, there was no significant difference between the 3 groups （P〉0.05）, the rate of caries incidence in the experimental group B was significantly higher than group A during the observation period after 12 months （P〈0.05）. Caries incidence in both group A and B was lower than the control group, with significant difference （P〈0.05）. CONCLUSIONS： Both duraphat fluoride varnish and fluoride foam prove to be effective in caries prevention. Moreover, considering other factors such as safety, convenience and cost, fluoride protector will be an even better choice in practical use.