MRI对成人早期何杰金病放疗效果的监测

The evaluated value of MRI signal intensity before and after radiotherapy of adult early-stage Hodgkin's disease

目的测量60例成人早期何杰金病(HD)放疗前后磁共振成像(MRI)信号强度(SI)的变化,而准确评估放疗对成人早期HD的疗效。方法应用MRI的自动测量系统,在放疗前后分别测量肿瘤、皮下脂肪及肌肉的SI,分别用脂肪和肌肉的SI除以肿瘤的相应测量值而得到标准化值。结果放疗后肿瘤SI的脂肪和肌肉的标准化值的均数及标准差分别为(0.4±0.3)和(1.8±1.2),比放疗前的标准化值明显减少(P<0.01)。结论MRISI的测量可准确评估成人早期HD的放疗效果,其T2加权图象(T2WI)可对纤维化组织和残留或复发的肿瘤组织作出鉴别。

Objectiv e To evaluate the curative effect of radiotherapy of adult early-stage Hodgkin's disease (HD)in60cases,by comparing signal intensity(SI)of MRI after and before radiotherapy.Methods By using the automatic measurement system of MRI,the SI of tumors,subcutaneous fat and muscles were measured before and after radiotherapy.The standardized value was obtained by dividing the SI of tumor into that of fat and muscle.Results After radiotherapy the standardized values of tumor SI of fat,and of muscle were(0.4±0.3)and(1.8±1.2)respectively.They were decreased obviously than those before radiotherapy(P<0.01).Conclusion The measurement of MRI SI can accurately evaluate the curative effect of HD;T 2 -weighted images of MRI are most helpful in distinguishing fibrotic tissue from recurrent tumor tissue.