便携式尿碘自动分析仪的研制

A portable analyzer for determination of iodine in human urine

介绍了应用离子色谱和安培检测的原理快速测定尿碘的便携式尿碘自动分析仪的研制—从信号处理、采样、到数据分析 ;给出了用计算机技术实现尿碘测定的软件及硬件原理框图 ,以及对色谱图的分析方法。仪器具有无干扰、灵敏度高、方法简便等特点。浓度为 2 0～ 2 0 0 μg L和 2 0 0～ 15 0 0 μg L范围内 ,其浓度与峰面积响应值之间存在良好的线性关系 (相关系数分别为 0 9996和 0 9998)。最低检测限为 10 μg L ,重复测定相对标准偏差 <5 % ,尿标样测定相对误差 <3%。 15人份尿样 ,测定结果为 116 0～ 10 79μg L。

A instrument based on principle of ion chromatography and amperometric detector for quick determination of iodine in urine are introduced in this paper, which covers from signal collection and treatment to data analysis. It presents the principle of hardware and software method to obtain the determination by using computer technology as well as the method of analysis of chromatogram. The instrument possess advantage of single, sensitive and simple .Both of tow stages of calibration curve for iodine 20-150 and 200-1500 μg/L respectively showed good linearity with r>0.999 .The detection limit of iodine was 10 μg/L(signal to noise ratio 3∶1).The relative standard deviation was less than 5%(n=4),The relative error of measuring urine reference material was less than 3%. Range of iodine in concentration 15 human urine samples by this method was 116.0-1079 μg/L