大豆蛋白抗原表位及生物脱敏方法研究进展

Development in Soybean Protein Antigen Epitopes and Biological Methods of Reducing Allergenicity

蛋白质是人类能量和营养物质的重要来源,然而它的部分组分会导致敏感个体发生过敏反应。该文综述了与大豆蛋白发生过敏反应有关的抗原表位,对抗原表位的研究将为表位疫苗的研发及特异性抗体的鉴定等提供参考依据;此外详细总结了酶解和发酵等生物脱敏方法,这将为低致敏大豆制品的开发奠定理论基础。

Protein is an important source of human energy and nutrients, however, some of the protein components can cause allergic reactions in sensitive individuals. In this paper, review the epitopes related to the hypersensitivity reaction of soybean protein. The study of antigen epitopes will provide reference for the development of epitope vaccines and the identification of specific antibodies. In addition, fermentation and hydrolysis as biological desensitization method are summarized detailedly,which will lay a theoretical foundation for the development of low-sensitized soybean products.