炙甘草汤治疗冠心病不稳定型心绞痛临床疗效观察

Clinical Observation on Zhigancao Decoction in Treatment of Unstable Angina Pectoris of Coronary Heart Disease

目的观察炙甘草汤治疗不稳定型心绞痛的临床疗效。方法 64例不稳定型心绞痛患者随机分为两组,每组32例。对照组仅给予常规药物治疗;治疗组在常规药物治疗基础上加用中药炙甘草汤加减,每次200mL,每日2次口服,疗程4周。结果对于不稳定型心绞痛,治疗组总有效率明显高于对照组(P<0.05);在心电图疗效观察上,治疗组总有效率明显高于对照组(P<0.05);两组对血脂、血流变的影响,治疗组均优于对照组,差异有统计学意义(P<0.05)。结论炙甘草汤加减治疗不稳定型心绞痛安全有效。

Objective To observe the clinical efficacy of Zhigancao decoction in treatment of unstable angina pectoris. Methods 64 cases of patients with unstable angina were randomly divided into control group and treafment groups, 32 cases in each group. Control group was given conventional drug; treatment group receiced modified Zhigancao decoction on the basis of control group, 200mL per time, 2 times per day, the treatment course was 4 weeks. Results Inthe case of unstable angina, the total effective rate of treatment group was significantly higher than that of control group （P〈0.05）. In the observation of elec- trocardiogram effect, the total effective rate of treatment group was significantly higher than that of control group （P〈0.05）. The blood lipids, blood theology of treatment group were better than those of control group, the differences were statistically significant （P〈0.05）. Conclusion Zhigancao decoction is safe and effective in treatment of unstable angina pectoris.