清热止痛方治疗急性牙髓炎的疗效及其对根尖组织的影响

Effect of Qingre Zhitong Decoction in the Treatment of Acute Pulpitis and Periapical Tissue

目的分析清热止痛方治疗急性牙髓炎的疗效及其对根尖组织的影响。方法选择2014年11月至2015年8月间在本院进行急性牙髓炎治疗的患者共70例,按随机数字表法分为两组,对照组和观察组各35例。对照组采用根管治疗术法,观察组在此基础上加用清热止痛方治疗。比较两组患者治疗效果、疼痛程度,相关指标(白细胞、肌酐、谷丙转氨酶)及牙根扛折性。结果观察组总有效率及疼痛程度显著优于对照组(P<0.05);治疗前后两组的肌酐、谷丙转氨酶水平无明显变化(P>0.05);而白细胞治疗前后及组间对比,差异有统计学意义(P<0.05);治疗后观察组牙根抗折性能明显提高,与对照组有显著差异(P<0.05)。结论清热止痛方治疗急性牙髓炎安全有效,副作用小,能有效缓解患者剧烈疼痛,提高患者机体免疫功能。

Objective To study the effect of Qingre Zhitong decoction for the treatment of acute pulpitis and periapical tissue.Methods The 70 cases of patients with acute pulpitis from November 2014 to August 2015 were randomly divided into the control group and the observation group according to the random number table,35 cases in each group.The control group was treated with root canal therapy,and the observation group was treated with the Qingre Zhitong decoction on the basis of control group.The curative effect,pain degree,related indicators（white blood cell,creatinine,glutamic-pyruvic transaminase）and root fracture resistance were compared in the two groups.Results The total effective rate and pain degree of observation group were significantly better than that of control group（P 0.05）.Before and after treatment,there was no significant change in creatinine,alanine aminotransferase（ALT） levels in the two groups（P〈0.05）,but the white blood cells were statistically significant（P〈0.05） before and after treatment,and between the two groups.After treatment,the root fracture resistance of observation group was significantly improved than the control group（P〈0.05）.Conclusion Qingre Zhitong decoction is safe and effective in the treatment of acute pulpitis,and with small side effect.The decoction can effectively relieve the severe pain of patients improve the immune function of patients.