小儿特发性间质性肺炎的临床分析

Clinical Analysis on Idiopathic Interstitial Pneumonia in Children

目的:探讨小儿特发性间质性肺炎的临床特点与疗效。方法:在某院中选取2015年5月~2016年5月所收治的25例小儿特发性间质性肺炎患者作为观察组,将同期体检的25名儿童设为对照组,进行比较分析。结果:两组的血白细胞、C-反应蛋白(CRP)、乳酸脱氢酶(LDH)、血沉(ESR)情况相比,观察组的水平明显高于对照组;SaO2相比,对照组的水平高于观察组(P<0.05),有统计学意义。观察组的血清肿瘤坏死因子-α(TNF-α)、白介素-8(IL-8)水平低于对照组(P<0.05),有统计学意义。结论:小儿特发性间质性肺炎病症容易反复,常存在漏诊、误诊状况,要利用影像学检查和临床表现,及早诊断、及早治疗。

Objective： To investigate the clinical characteristics and therapeutic effect of idiopathic interstitial pneumonia in children. Methods. 25 cases of children with idiopathic interstitial pneumonia in our hospital from May 2015 to May 2016 were selected as the observation group and 25 children received physical ex- amination in the same period were set as the control group. Results： The level of white blood cells, C-reactive protein （CRP）, lactate dehydrogenase （LDH）, erythrocyte sedimentation rate （ESR） in the observation group is significantly higher than that of the control group, the level of SaO2 in the control group is higher than those in the observation group（P〈0.05）, with statistical significance. The level of tumor necrosis factor alpha （TNF-alpha） of serum and interleukin-8 （IL-8） in the observation group were lower than those in the control group （P〈0.05）, with statistical significance. Conclusion： The disease of idiopathic interstitial pneumonia in children is prone to be repeatedly, and missed diagnosis, or misdiagnosis. The iconography and clinical manifestations were required for diagnosis so it needs early diagnosis and early treatment.