2型糖尿病经格列美脲治疗的有效性及药理探究

Effectiveness and Pharmacology of Glimepiride in the Treatment of Type 2 Diabetes Mellitus

目的:分析格列美脲治疗2型糖尿病的效果及药理作用。方法:随机选择2014年11月~2016年11月在某院接受治疗的2型糖尿病患者50例参与研究,随机平均分成两组,对照组利用药物格列齐特治疗,观察组选择药物格列美脲治疗,比较两组效果。结果:观察组治疗总有效率为96%,对照组总有效率为68%;观察组治疗后HbA1c、2hPG、FPG水平明显低于对照组(P<0.05)。结论:格列美脲治疗2型糖尿病效果明显,能够明显改善血糖水平,不会影响治疗安全性,值得推广。

Objective：To analyze the effect and pharmacology of glimepiride in the treatment of type 2 diabetes.Methods：50 patients with type 2 diabetes treated in a hospital from November 2014 to November 2016 were randomly selected and divided into two groups.The control group was given drug gliclazide treatment, and the observation group was given drug glimepiride treatment,then the effect between the two groups was compared.Results：The total effective rate of observation group was 96%, the total effective rate of control group was 68%, and the HbAlc, 2hPG and FPG levels in the observation group were significantly lower than those in the control group （P〈0.05）.Conclusion：Gglimepiride in the treatment of type 2 diabetes has obvious effect,which can significantly improve the blood glucose level,will not affect the safety of the treatment, and is worthy of promotion.