养血柔肝针法治疗卒中后抑郁临床研究

Clinical Study of Yang Xue Rou Gan Needling in Treating Post-stroke Depression

目的评价养血柔肝针法治疗卒中后抑郁的临床疗效。方法将150例卒中后抑郁患者按随机数字表法分为观察组、对照组,每组75例。两组在相同基础治疗的同时,对照组采用盐酸氟西汀治疗,观察组加用养血柔肝针法治疗,疗程均为每日2次,6 d为1个疗程,休息1 d后,继续第2个疗程,共计4星期。治疗前后进行24项汉密尔顿抑郁量表(HAMD)、改良爱丁堡-斯堪的那维亚神经功能缺损评分量表(MESSS)、日常生活活动能力量表(ADL,Barthel指数,BI)评分进行评定。结果两组患者治疗后HAMD评分、MESSS评分、BI指数方面,与同组治疗前比较差异有统计学意义(P<0.05),提示两组患者治疗后抑郁症候均有改善,治疗后两组间比较差异有统计学意义(P<0.01),说明观察组抗抑郁疗效优于对照组。结论养血柔肝针法可以显著改善卒中后抑郁症患者的抑郁程度及神经功能缺损程度。

Objective To evaluate the clinical efficacy of Yang Xue Rou Gan （blood-nourishing and liver-soothing） needling method in treating post-stroke depression. Method A total of 150 patients with post-stroke depression were divided into an observation group and a control group by using the random number table, 75 cases each. In addition to the same basic treatment, the control group was intervened by Fluoxetine hydrochloride, while the observation group received Yang Xue Rou Gan needling method, twice every day, 6 d as a course at 1-day interval, for 4 weeks in total. Before and after the intervention, 24-item Hamilton Depression Scale （HAMD）, Modified Edinburgh-Scandinavian Stroke Scale （MESSS）, and activities of daily living [ADL, Barthel Index （BI）] were evaluated Result After the intervention, HAMD, MESSS, and BI scores were significantly changed in both groups （P〈0.05）, indicating that the two groups both had improvements in depression symptoms and signs; there were significant differences between the two groups （P〈0.01）, suggesting that the observation group had a more significant efficacy in treating depression. Conclusion Yang Xue Rou Gan needling method can notably improve the depression and neural deficit level in post-stroke depression patients.