健脾除湿止痒方治疗湿疹28例

Invigorating Spleen and Removing Dampness for Relieving Itching Prescription in the Treatment of Eczemafor 28 Cases

目的研究健脾除湿止痒方对脾虚湿盛型湿疹的临床疗效。方法选取56例脾虚湿盛型湿疹患者,随机分为对照组与观察组,每组28例。观察两组患者的症状和体征,采用湿疹面积及严重度指数评分法(EASI)与瘙痒评分进行评价。结果观察组患者治疗后EASI评分明显低于对照组(1.14±0.75 vs 2.69±1.04),差异有统计学意义(P<0.05);观察组患者治疗后瘙痒评分明显低于对照组(0.64±0.38 vs 1.54±0.47),差异有统计学意义(P<0.05);随访6个月,两组复发率比较(10.71%vs 32.14%),差异有统计学意义(P<0.05)。结论健脾除湿止痒方能够显著减少脾虚湿盛型湿疹患者瘙痒及皮损症状,还能减少复发率。

Objective To research the clinical effect of invigorating spleen and removing dampness for relieving itching prescription in the treatment of eczema of damp abundance due to deficiency of spleen. Method 56 patients with eczema of damp abundance due to deficiency of spleen were selected and randomly divided into the control group and the treatment group. There were 28 patients in each group. The symptom and sign which evaluate with Eczema Area and Severity Index （EASI） and pruritus score in every patient were observed. Result The EASI score of the treatment group was significantly lower that of the control group （ 1.14±0. 75 vs 2.69±1.04 ） （ P 〈 0. 5 ）. The pruritus scores in treatment group were also obviously lower than that of the control group （0. 64±0. 38 vs 1.54±0.47 ） （ P 〈 0.5 ）. The differences of recurrent rate between these two groups were significant after 6 months following-up（P 〈 0. 5）. Conclusion The invigorating spleen and removing dampness for relieving itching prescription can reduce the symptom of pruritus and rash in eczema which belong to damp abundance due to deficiency of spleen besides the recurrent rate.