梗阻性黄疸肾脏损伤机制的研究进展

Research progress of the mechanism of renal injury in obstructive jaundice

梗阻性黄疸(obstructive jaundice,OJ)是由各种原因引起的细小胆管、肝总管或胆总管的机械性梗阻所致,是临床上肝胆外科方面常见的疾病。它会对全身各个脏器造成不同程度的损伤,肾脏是对由OJ引起的各种损伤因素最为敏感的器官之一。OJ中肾脏损伤的机制涉及很多因素,本文旨在探讨不同损伤因素对于OJ时肾脏的损伤及其损伤机制。

Obstructive jaundice （OJ） is a common disease in clinical biliary tract surgery. It is caused by obstruction in hepaticduct or choledochus, and it will cause different degrees of damage to the organs of the body. The kidney is one of the most sensitive organs of all kinds of damage caused by OJ. The mechanism of renal injury in OJ is related to many factors, and the purpose of this study was to investigate the mechanism of renal injury and its mechanism in the injury of OJ with different injury factors.