舒芬太尼复合地佐辛用于二次剖宫产术后镇痛的临床疗效及其安全性分析

Analysis of clinical efficacy and safety of Sufentanil combined with Dezocine for postoperative analgesia of secondary cesarean section

目的探讨舒芬太尼复合地佐辛在二次剖宫产术后镇痛中的临床疗效及其安全性。方法选择我院2015年2月~2016年2月收治的56例二次剖宫产产妇,采用随机数字表法分成A组(30例)与B组(26例)。A组术后镇痛采用舒芬太尼复合地佐辛,B组术后镇痛采用地佐辛。比较两组产妇镇痛后的VAS评分以及不良反应情况。结果A组口述疼痛以及VAS评分均明显低于B组,差异有统计学意义(P<0.05)。A组的不良反应发生率为3.33%,明显低于B组的23.07%,差异有统计学意义(P<0.05)。结论采用舒芬太尼复合地佐辛术后镇痛方法能够有效降低二次剖宫产产妇VAS评分,减轻产妇术后疼痛感,降低不良反应发生率,具有一定的临床应用价值。

Objective To investigate the clinical efficacy and safety of Sufentanil combined with Dezocine in the postoperative analgesia of secondary cesarean section.Methods From February 2015 to February 2016,56 puerperae after second cesarean section admitted into our hospital were selected.By a random number table method,they were divided into group A （n=30） and group B （n=26）.In group A,Sufentanil combined with Dezocinewas used for postoperative analgesia,while in group B,Onlydezocine was applied.The visual analogue scale （VAS） score after analgesia and incidence rate of adverse reactions in puerperae were compared between the two groups.Results The oral pain and VAS score in group A were both lower than that in group B,with statistical differences （P〈0.05）.The incidence rate of adverse reactions in group A was 3.33%,which was significantly lower than that in group B accounting for 23.07%,with a statistical difference （P〈0.05）.Conclusion The application of Sufentanil combined with Dezocinefor postoperative analgesia can effectively decrease the VAS scorein puerperae after second cesarean section,alleviate the postoperative painful sensation,and reduce the incidence rate of adverse reactions,which has a certain clinical value.