高渗盐水联合布地奈德雾化吸入治疗小儿毛细支气管炎的效果观察

Efficacy of hypertonic saline combined with Budesonide Inhalation in the treatment of capillary bronchitis in children

目的探讨3%高渗盐水联合布地奈德雾化吸入治疗小儿毛细支气管炎的效果。方法选取2015年1月~2017年1月我院收治的250例小儿毛细支气管炎患儿作为研究对象,按住院床号末位奇偶数均分为两组,每组各125例,住院期间都予抗感染、止咳和对症治疗。治疗组患儿给予3%高渗盐水2 ml联合布地奈德0.5 mg雾化吸入治疗,对照组患儿给予生理盐水2 ml联合布地奈德0.5 mg雾化吸入治疗。比较两组患儿的喘息、咳嗽、肺部啰音消失时间及住院时间。比较两组患儿7 d后的治疗效果。结果治疗组患儿的咳嗽、喘憋、肺部啰音消失时间及住院天数均短于对照组,差异有统计学意义(P<0.05)。治疗组患儿的治疗总有效率高于对照组,差异有统计学意义(P<0.05)。结论 3%高渗盐水联合布地奈德雾化吸入治疗小儿毛细支气管炎的效果显著,值得临床推广。

Objective To investigate the effect of 3% hypertonie saline combined with Budesonide Inhalation on capillary bronchitis.Methods Totally 250 cases of children with capillary bronchitis treated in our hospital from January 2015 to January 2017 wererandomly divided into two groups according to odd or even of the hospital bed last one number,each group has 125 cases.During hospitalization,children were both given anti-infection,cough and symptomatic treatment.The therapy group was treated with 3% hypertonic saline 2 ml cmobined with 0.5 mg Budesonide Inhalation the control group was treated with 0.9% saline solution 2 ml combined with 0.5 mg of Budesonide Inhalation.The wheezing remission time,moist crackles disappearance time and the length of hospital stay between the two groups were compared.The treatment effect of 7 d was compared between the two groups.Results The wheezing remission time,moist crackles disappearance time and the length of hospital stay of children in the therapy group were shorter than those in the control group,and the differences were statistically significant （P〈0.05）.The total treatment effective rate in the ther- apy group （97.00%） was higher than that in the control group （88..00%）,and the difference was statistically significant （P〈0.05）.Conclusion The effect of 3% hypertonic saline combined with Budesonide Inhalation therapy in the treatment of capillary bronchitis in children is significant,and it is worthy of clinical promotion.