HPV分型检测及其在宫颈病变中的应用与临床意义评估

Application and Clinical Significance of HPV Typing in Cervical Lesions

目的探究HPV分型检测及其在宫颈病变中的应用与临床意义。方法选择2015年5月—2016年5月我院符合研究标准的52例女性患者为研究对象,实施HPV分型检测,对结果进行全面分析。结果宫颈炎,癌前病变(CIN I-III)和宫颈癌的HPV阳性情况对比,差异有统计学意义,其阳性率分别为43%、71%、80%、88%和100%。在HPV感染者中,高危型与单一感染为主要类型。结论HPV感染和宫颈病变发生情况存在较高关联性。对疑似者实施HPV检测有利于筛查各类宫颈病变,对于宫颈癌预防和治疗来讲,有着相当重要的现实意义。

Objective To explore the application and clinical significance of HPV typing and its application in cervical lesions. Methods From May 2015 to May 2016, 52 female patients in our hospital were selected as the research object, and the HPV typing was carried out to analyze the results in an all-round way. Results The positive rate of HPV in inflammatory, cervical precancerous lesion （CIN I-III） and cancer was statistically significant. The positive rates of each group were 43%, 71%, 80%, 88% and 100%, respectively. Among the HPV infected people, high risk and single infection are the main types. Conclusion There is a high correlation between the incidence of HPV infection and the occurrence of cervical lesions. It is of great practical significance for the prevention and treatment of cervical cancer to carry out HPV detection for suspected people.