莫西沙星治疗慢性支气管炎急性发作的临床分析

Clinical Analysis of Moxifloxacin in the Treatment of Acute Exacerbation of Chronic Bronchitis

目的研究莫西沙星治疗慢性支气管炎急性发作的临床疗效。方法选取90例慢性支气管炎急性发作患者,随机分为对照组和观察组(n=45)。对照组给予罗红霉素进行治疗,观察组则给予莫西沙星。观察对比治疗总有效率、临床症状缓解时间及不良反应发生率。结果观察组治疗总有效率95.56%,高于对照组77.78%,临床症状缓解时间少于对照组,不良反应发生率2.22%,低于对照组17.78%,差异具有统计学意义(P<0.05)。结论莫西沙星治疗慢性支气管炎急性发作效果显著,可有效减轻临床症状及不良反应发生率。

Objective To study the clinical efficacy of moxifloxacin in the treatment of acute exacerbation of chronic bronchitis. Methods 90 patients with acute exacerbation of chronic bronchitis were randomly divided into control group and observation group （n=45）. The control group was treated with roxithromycin, while the observation group was treated with moxifloxacin. The total effective rate of treatment, clinical symptoms and adverse reaction between two groups were observed and compared. Results The total effective rate 95.56% in the observation group was higher than that in the control group 77.78%, the clinical symptom relief time was shorter than that in the control group, and the incidence of adverse reactions 2.22% was fewer than that in the control group 17.78%, the difference was statistically significant （P 〈0.05）. Conclusion Moxifloxacin treatment for acute exacerbation of chronic bronchitis can obtain significant effect, and effectively reduce the incidence of clinical symptoms and adverse reactions.