摘要
以氯乙酸和无水乙醇为原料,环己烷为带水剂,采用反应精馏的方法合成氯乙酸乙酯。考察了催化剂种类、催化剂用量、原料配比、环己烷用量以及有效板数对反应的影响。结果表明,较佳的反应条件为:D8099-T强酸性阳离子交换树脂为催化剂,用量为氯乙酸质量的1.00%,n(氯乙酸)∶n(无水乙醇)=1∶3,环己烷用量为80m L/mol氯乙酸,有效板数为14。在该反应条件下,氯乙酸的转化率为100%,氯乙酸乙酯的收率为97.77%。
The synthesis of ethyl chloroacetate from chloroacetic acid and ethyl alcohol by reactive distillation using cyclohexane as water-carrying agent was studied. The effects of catalyst types and dosage, reactants ratio, cyclohexane amount and tray number on reaction were investigated. The results indicate that the optimal reaction conditions are as follows: D8099-T strong- acid cation resin as catalyst, mass ratio of catalyst to chloroacetic acid of 1.0%, molar ratio of chloroacetic acid to ethanol of 1 : 3, cyclohexane 80 mL per mole chloroacetic acid, and tray number of 14. Under above conditions, the yield of ethyl chloroacetate and conversion of chloroacetic acid reached 97.77% and 100%, respectively.
出处
《天然气化工—C1化学与化工》
CSCD
北大核心
2017年第6期81-85,共5页
Natural Gas Chemical Industry
关键词
氯乙酸乙酯
强酸性阳离子交换树脂
反应精馏
带水剂
ethyl chloroacetate
strong-acid cation exchange resin
reactive distillation
water-carrying agent