云南省家鼠鼠疫疫源地静息期鼠疫指示动物血清流行病学调查

Sero-epidemiological survey of indicator animals in the quiescent stage of domestic rodent-maintained epidemic focus of plague in Yunnan province

目的通过调查云南省家鼠鼠疫疫源地静息期鼠疫指示动物血清F1抗体阳性率,探讨鼠疫在静息期内的隐性流行情况和流行动态。方法于2015年11月11日至2016年7月22日,在云南省澜沧、弥渡、宜良和梁河县采集鼠疫指示动物样本,采用IHA对鼠疫指示动物(犬和猫)血清进行F1抗体的实验室检测。结果在云南省澜沧、弥渡、宜良和梁河县鼠疫历史流行区采集动物血清393份,其中犬血清387份,猫血清6份,鼠疫指示动物血清F1抗体检测均为阴性。结论该地区动物鼠疫流行的可能性较小,鼠疫疫源地静息期鼠疫指示动物血清流行病学调查在鼠疫防控工作中具有重要意义。

Objective By investigating the positive rate of F1 antibody in indicator animals in the quiescent stage ofdomestic rodent-maintained epidemic focus of plague in Yunnan province, the hidden epidemic situation and dynamic inthe quiescent stage of plague were discussed. Methods From November 11, 2015 to July 22, 2016, the sample collectionof plague indicator animals was carried out in Lancang, Midu, Yiliang, and Lianghe counties in Yunnan province, andemployed the IHA laboratory testing of F1 antibody for the serum-collection of plague indicator animals（dog/cat）.Results In four historical epidemic areas of plague of Lancang, Midu,Yiliang, and Lianghe counties in Yunnan province,393 samples of animal sera were collected, including 387 dogs and 6 cats. The serum-collections of plague indicator animal＇s F1 antibody detection tested all negative. Conclusion The possibility of the plague epidemic in this region was meager,and sero-epidemiological survey of indicator animals in the quiescent stage makes a huge difference in the plagueprevention and control work.