基于中医传承辅助平台的藏医药治疗胃痛用药规律分析

Analysis on Medication Rules of Tibetan Medicines in Treating Stomachache Based on Traditional Chinese Medicine Inheritance Assistance System

目的:采用中医传承辅助平台软件分析藏医药治疗胃痛方剂的组方规律。方法:收集《部颁标准·藏药分册》、《藏药标准》、《常用藏成药诠释》等法定标准及著作中治疗胃痛的藏药方剂,应用中医传承辅助平台软件,采用改进互信息法、复杂系统熵聚类、无监督的熵层次聚类等数据挖掘方法,分析藏医治疗胃痛方剂中常用药物、组方规律、核心组合及发现新方。结果:整理出治疗胃痛的藏医方剂共94首,涉及228味藏药,使用频次7次及以上的藏药共34种,获得治疗胃痛药对及核心组合52个、新处方13个。结论:藏医治疗胃痛的核心药物为荜茇、诃子、藏木香、寒水石等,常用的核心组合为寒水石-藏木香和荜茇-藏木香。本文为这些药物的临床应用和治疗胃痛的新药开发提供了参考依据。

Objective： To analyze the medication rules of Tibetan medicines in the treatment of stomachache based on Traditional Chinese Medicine Inheritance Support System （TCMISS）. Methods： Prescriptions for treating stomachache were collected from ＂Department Standard＂, ＂Drug Standards of Tibetan Medicines＂, ＂Interpretation of Commonly Used Tibetan Medicine＂ and so on. The improved mutual information, complex system entropy clustering and unsupervised hierarchical clustering entropy methods of TCMISS were applied to analyze the commonly used drugs, composition rules, core combination and discovery of new prescriptions. Results： 94 prescriptions used for stomachache were included in this study involving 228 Tibetan herbs, 34 Tibetan medicines used equal to or more than 7 times. Moreover, 52 core combinations and 13 new prescriptions were evolved and obtained. Conclusion： The core Tibetan medicines in the treatment of stomachache are Fructus Piperis Longi, Terminalia chebula Retz, Radix Inulae Racfmosae, Gypsum Rubrum, etc. The commonly used core combinations are Gypsum Rubrum- Radix Inulae Racfmosae and Fructus Piperis Longi-Radix lnulae Racfmosae. This article provides a reference for the clinical application of these drugs and development of new drugs in the treatment of stomachache.