氯吡格雷与阿司匹林治疗冠心病的临床效果和不良反应

Clinical Efficacy and Adverse Reactions of Clopidogrel and Aspirin in the Treatment of Coronary Heart Disease

目的:探讨氯吡格雷与阿司匹林治疗冠心病的临床效果。方法:回顾性分析笔者所在医院2015年2月-2016年12月收治的100例冠心病患者临床资料,按照用药方法分为对照组和研究组,每组50例,对照组予以阿司匹林治疗,研究组予以氯吡格雷治疗。比较两组患者临床疗效及不良反应发生情况。结果:研究组临床有效率(96.00%)显著高于对照组(76.00%),差异有统计学意义(P<0.05)。研究组不良反应发生率(6.00%)显著低于对照组(26.00%),差异有统计学意义(P<0.05)。结论:相较于阿司匹林,氯吡格雷治疗冠心病疗效更确切,不良反应发生率更低。

ObjectiveTo investigate the clinical effect of Clopidogrel and Aspirin in the treatment of coronary heart disease.Method：A retrospective analysis of the clinical data of 100 cases of patients with coronary heart disease in our hospital from February 2015 to December 2016 were applied,according to treatment methods were divided into control group and study group,50 cases in each group.The control group was given Aspirin treatment,the study group was given Clopidogrel treatment.The clinical efficacy and adverse reactions were compared between the two groups.Result： The clinical effective rate of the study group（96%） was significantly higher than that of the control group（76%）（P〈0.05）.The incidence of adverse reactions in the study group（6%）was significantly lower than that in the control group（26%）（P〈0.05）.Conclusion：Clopidogrel treatment of coronary heart disease compared with Aspirin,the curative effect is more accurate,the incidence of adverse reactions is lower.