广西居民食用植物油黄曲霉毒素B_1膳食暴露评估

Dietaryexposure assessment of aflatoxin B_1 in edible vegetable oil consummed by Guangxi residents

目的了解广西居民食用植物油的黄曲霉毒素B1(AFB1)暴露风险。方法结合广西居民食用植物油中AFB1污染状况和人群摄入量的调查结果,应用点评估方法对植物油中AFB1膳食暴露情况进行了分析。结果植物油样品AFB1含量范围为0.50~320μg/kg。花生油AFB1检出率为78.08%(114/146),超标率为31.51%(46/146),平均含量30.80μg/kg。人群每日膳食暴露量为17.33 ng/kg·BW,导致乙肝表面抗原(HBs Ag)阳性人群原发性肝癌(HCC)发病数为45.67例/107人·年。定型包装花生油中AFB1平均含量为6.33μg/kg,低于国家安全标准,处于安全范围;散装花生油AFB1平均含量为41.50μg/kg,高出国家标准1.08倍,人群每日膳食暴露量25.59 ng/kg BW,导致HBs Ag阳性人群HCC发病数为67.56例/107人·年。结论监管部门应采取有力的措施整治作坊式生产的散装花生油的食品安全问题,对于散装花生油应优先采取风险管理措施,同时做好人群健康饮食习惯的卫生宣传教育,控制油脂的摄入量。

Objectives To know the exposure of aflatoxin B1(AFB1) in edible vegetable oil consummed by Guangxi residents.Methods The point assessment method was applied to analyses AFB1 exposure in Guangxi resisdents considering with the pollution status of AFB1 in ediable peanut oil and food intake.Results The contentof AFB1 in all vegetable oil samples detected was 0.50~320 μg/kg. The detection rate of AFB1 in peanut oil was78.08%(114/146), which was much higher than that of the other vegetable oils. In the peanut oil there were 31.51%(46/146) of samples exceed the standard of AFB1 content, and the average content was 30.80 μg/kg. The exposure dosage of AFB1 in residents was 17.33 ng/kg BW everyday. This exposure dosage of AFB1 can cause 45.67 case of primary liver cancer(HCC) in 10 million person year in hepatitis B surface antigen(HBs Ag) positivepersons. As for stereotypes packaged peanut oil, the average content of AFB1 was 6.33 μg/kg, which was in the scope of security;while the the average content of AFB1 in bulk peanut oil was 41.50 μg/kg, higher than government standard. The exposure of AFB1 from bulk peanut oil in the residents was 25.59 ng/kg BW, consequently, itcan cause 67.56 case of HCC in 10 million person year in HBs Ag positive persons.Conclusions The strengthen monitoring measures should be taken in bulk peanut oil production and sail and the healthy eating habits fo residents be promoted.