大环多胺金属配合物的超分子识别与检测

Supramolecular Recognition and Detection of Macrocyclic Polyamine Metal Complexes

金属离子是分子组成物质中的金属元素,它与环境科学及生命科学等众多学科存在密切联系,于是文中提出设计一种大环多胺金属配合物,利用荧光传感超分子体系对金属离子客体进行识别与检测。首先,由于大环多胺配体的成环氮原子具备强配位能力,利用Richman-Atkins环化合成法初步合成基础中间化合物,通过控制反应物的摩尔量获得收率高的关键中间体,并与二价铜离子Cu(Ⅱ)通过合适的反应温度及反应溶剂形成多功能大环多胺金属配合物;其次,依据待分析配合物反应部位的特殊性质,利用荧光传感体系对金属离子客体实现识别及检测过程,将荧光团作为发射荧光的功能基团,离子受体当作金属离子识别与检测的接受团,通过光诱导电子转移PET体系完成对超分子的识别过程。

Metal ions are metal elements in molecular material, is closely related to many areas of science and environmental science and life science, so the paper proposed a design of macrocyclic polyamine complexes, metal ions on the object of supramolecular recognition and detection using fluorescence sensing system. First of all, because the ring nitrogen atom macrocyclic polyamine ligands have strong coordination ability, synthetic method of preliminary synthesis foundation of intermediate compounds by Richman-Atkins ring, obtained the key intermediate of high yield by the molar amount of the reactants,and Cu(II) ions by reaction temperature and solvent suitable form function macrocyclic polyamine metal complexes; secondly, according to the special nature of complex reaction site for analysis of metal ions to realize object recognition and detection process using fluorescence sensing system, the fluorophore as functional groups of fluorescence emission, ion as metal ion receptor recognition and detection of the receiving group, through the photoinduced electron transfer of PET system the recognition process of supramolecular.