经产妇妊娠期糖尿病危险因素分析

Analysis of risk factors for gestational diabetes of multipara

目的研究经产妇妊娠期糖尿病(gestational diabetes mellitus,GDM)危险因素。方法回顾性分析2014年1月至2014年8月济宁医学院附属医院产检诊断为GDM的经产妇190例,同期选择177例非妊娠期糖尿病经产妇作为对照,对其危险因素进行logistics回归分析。结果单因素分析发现年龄、孕前体重指数、糖尿病家族史、巨大儿分娩史、孕次、不良孕产史、多囊卵巢综合症是经产妇GDM的危险因素,logistics回归分析发现孕前体重指数每增加1kg/m2,经产妇发生GDM的风险增加23%[OR=1.23 95%CI(1.09,1.38)P=0.001],年龄、糖尿病家族史、巨大儿分娩史、孕次、不良孕产史、多囊卵巢综合症不再是危险因素。结论孕前体重指数是经产妇GDM的独立危险因素。

Objective To explore the risk factors for gestational diabetes of multipara. Methods Retrospective analysis from January 2014 to August 2014 in the Affiliated Hospital of Jining Medical University were made for prenatal diagnosis of 190 cases with the Multipara l gestational diabetes and 177 cases of gestational diabetes multipara by contrast.The risk factors were analyzed by logistics regression analysis. Results Single factor analysis found that age,family history of diabetes,pre-pregnancy body-mass index,history of macrosomia delivery,gravidity,the histories of abnormal pregnancy,and polycystic ovarian syndrome were Multipara gestational diabetes risk factors. After logistic regression analysis,the index of pre-pregnancy body mass index increased by 1 kg/m2. The risk of gestational gestational diabetes increased by 23 percent per woman during pregnancy( OR = 1. 23,95% CI( 1. 09,1. 38) P = 0. 001). The age,family history of diabetes,large birth history,gravidity,the histories of abnormal pregnancy,and polycystic ovarian syndrome are no longer risk factors. Conclusion The pre-pregnancy body mass index is an independent risk factor for gestational diabetes during pregnancy of multipara.