期刊文献+

抵抗素在类风湿关节炎中的作用 被引量:2

The role of resistin in rheumatoid arthritis
下载PDF
导出
摘要 虽然类风湿关节炎的发生与炎症有着密不可分的关系,但肥胖现象越来越多的发生在类风湿关节炎患者身上,随着进一步研究发现,肥胖也是一种初级炎症状态,类风湿关节炎、脂肪、炎症三者之间的关系引起了人们的重视。因此,从与炎症相关的脂肪因子——抵抗素入手,作为构建肥胖与类风湿关节炎疾病关系的桥梁,分析其在类风湿关节炎中的作用。 Objective: Although the occurrence of rheumatoid arthritis has a inseparable relationship with inflammation,obesity is occurring in patients with rheumatoid arthritis increasingly.Obesity is also a primary inflammatory state with further research.It has aroused people's attention to the relationship between rheumatoid arthritis,obesity and inflammation.Resistin,one of the fat factors,is a linkage between obesity and rheumatoid arthritis.Thus,we analyzed the role of resistin in rheumatoid arthritis in this paper.
作者 关蕊 张杰
出处 《川北医学院学报》 CAS 2017年第6期956-959,共4页 Journal of North Sichuan Medical College
基金 国家科技部973计划 "脾主运化 统血"等脾藏象理论研究(2013CB531704)
关键词 抵抗素 炎症 脂肪 关节炎 类风湿 Resistin Inflammation Fat Arthritis Rheumatoid
  • 相关文献

参考文献7

二级参考文献111

  • 1罗远汉.健脾活血方治疗老年性类风湿关节炎32例[J].陕西中医,2008,29(8):997-999. 被引量:5
  • 2俞瑜,曾耀英,刘良,季煜华,肇静娴.雷公藤甲素对小鼠淋巴细胞体外活化的抑制作用[J].中药材,2005,28(6):499-502. 被引量:21
  • 3王勇,钟兵,方勇飞,李景怡,艾九松.青藤碱对类风湿关节炎患者炎性细胞因子及抗环瓜氨酸肽抗体的影响[J].第三军医大学学报,2005,27(15):1573-1575. 被引量:48
  • 4KERSHAW E E, FLIER J S. Adipose tissue as an endocrine organ [J]. J Clin Endocrinol Metab, 2004, 80: 2548-2556.
  • 5LICINIO J, CAGLAYNA S, OZATA M, et al. Phenotypic effects of leptin replacement on morbid obesity, diabetes mellitus, hypogonadism, and behavior in leptin-deficient adults [J]. Proc Natl Aead Sci, 2004, 101: 4531-4536.
  • 6QUEHENBERGER P, EXNER M, SUNDER-PLASSMANN R, et al. Leptin induces endothelin-1 in endothelial cells in vitro [J]. Cire Res, 2002, 90 (6):711 - 718.
  • 7PARK H Y, KWON H M, LIM H J, et al. Potential role of leptin in angiogenesls: leptin induces endothelial cell proliferation and expression of matrix metalloproteinases in vivo and in vitro[J]. Exp Mol Med, 2001, 33 (2):95-102.
  • 8TORRES M D, TORMO M A, CAMPILLO C, et al. Etiologic and cardiovascular risk factors in obese children from Extremadura in Spain. Their relationship with insulin resistance and plasma adipocytokine levels[J]. Rev Esp Cardiol, 2008,61(9) 5923-929.
  • 9MAEDA K, OKUBO K, SHIMOMURA I, et al. eDNA cloning and expression of a novel adipose specific collagen-like factor, apM1 (Adipose most abundant gene transcript)[J]. Biochem Biophys Res Commun, 1996, 221(2) ,286-289.
  • 10SPRANGER J, KROKE A, MOHLIG M, et al. Adiponectin and protection against type 2 diabetes mellitus [J]. Lancet, 2003, 361:226.

共引文献94

同被引文献15

引证文献2

二级引证文献8

相关作者

内容加载中请稍等...

相关机构

内容加载中请稍等...

相关主题

内容加载中请稍等...

浏览历史

内容加载中请稍等...
;
使用帮助 返回顶部