激光光凝对早产儿视网膜病变阈值前Ⅰ型的作用分析

Analysis the effect of laser photocoagulation on Ⅰ type of retinopathy of prematurity

目的:探讨激光光凝对早产儿视网膜病变阈值前I型的治疗效果。方法:对220例(380眼)Ⅰ型阈值前病变早产儿行810nm激光视网膜光凝手术,评价激光治疗效果,比较病变消退组和病变进展组患儿的治疗情况及术后不良反应发生情况。结果:220例患儿380只眼经激光光凝治疗后,病变完全消退376只眼(98.94%),病变消退但存在纤维增殖膜2眼(0.53%),病变进展至4A期2眼(0.53%)。I区和Ⅱ区病变疗效差异不具有统计学意义(P>0.05),病变消退组和病变进展组的患儿基本情况差异不具有统计学意义(P>0.05),未发生与治疗相关的不良反应。结论:激光光凝对早产儿视网膜病变阈值前I型具有较好的治疗效果。

Objective:To investigate the therapeutic effect of laser photocoagulation for typeⅠ pre-threshold retinopathy of prematurity.Methods:A retrospective analysis of 220 cases(380 eyes)of typeⅠ pre-threshold retinopathy of prematurity in our hospital in recent 5 years were conducted.They were under 810 nm laser photocoagulation surgery,and we evaluated the effect of laser treatment,comparing the basic information between regressed group and progressed group.Postoperative adverse reactions were also described.Results:220 cases(380 eyes)were treated with laser photocoagulation,ROP regressed completely in 376 eyes(98.94%),regressed but with a fibrous proliferative membrane in 2 eyes(0.53%),progressed to stage 4 Ain 2 eyes(0.53%).The difference of curative effect between zone Ⅰ and zone 2 was not statistically significant,the basic information between regressed group and progressed group was not statistically significant(P>0.05),no treatment-related adverse events occurred.Conclusion:The therapeutic effect of laser photocoagulation for typeⅠ pre-threshold retinopathy of prematurity is good.