炎症性肠病的诱导缓解策略

Strategies for remission induction of inflammatory bowel disease

炎症性肠病(inflammatory bowel disease,IBD)是一类多种病因引发的、异常免疫介导的肠道慢性及复发性炎症,主要包含溃疡性结肠炎和克罗恩病两个亚型,临床上呈现活动期与缓解期交替的特点.在疾病活动期,临床医师需要根据疾病的病变范围、严重程度、既往用药史及起病过程等制定合适的治疗方案,使疾病尽快由活动期转入缓解期.

Inflammatory bowel diseases（IBD） is an abnormal immune-mediated, chronic, recurrent gastrointestinal inflammatory disorder, which is caused by a variety of factors, including ulcerative colitis（UC） and Crohn＇s disease（CD）. IBD is characterized by alternating periods of relapse and remission. During the active period of IBD, clinicians usually formulate an appropriate medical management plan based on the disease activity, location, extent, and the medication history. In this way, remission can be induced as soon as possible. This paper summarizes the strategies for remission induction of IBD.