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丙戊酸钠预防重型颅脑损伤患者癫痫发作的临床观察 被引量:1

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摘要 目的观察丙戊酸钠预防重型颅脑损伤患者癫痫发作的临床效果。方法选取医院2013年3月-2016年3月收治的重型颅脑损伤患者120例,将其根据随机数字表法分为试验组和对照组各60例。对照组给予常规治疗,试验组在对照组治疗的基础上给予丙戊酸钠治疗。比较2组手术前后神经认知功能评分(Mo CA)及癫痫发生率。结果 2组患者的认知功能随着时间的推移均有所改善,试验组手术前、术后6 min和12 min Mo CA评分高于对照组,差异均有统计学意义(P<0.05)。试验组患者癫痫发生率为5.00%明显低于对照组的30.00%,差异有统计学意义(P<0.05)。结论丙戊酸钠可有效预防重型颅脑损伤术后癫痫发作,缓解患者术后神经功能下降,值得临床广泛推广应用。
出处 《临床合理用药杂志》 2017年第34期48-49,共2页 Chinese Journal of Clinical Rational Drug Use
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