摘要
Primary pigmented nodular adrenocortical disease (PPNAD) causes adrenocorticotropic hormone (ACTH)-independent Cushing's syndrome (CS),which is the most frequent endocrine manifestation of Carney complex (CNC).[1] In the disease process of PPNAD,both presadrenal glands are involved and feature small brown-black nodules separated by the atrophic adrenal cortex.
Primary pigmented nodular adrenocortical disease (PPNAD) causes adrenocorticotropic hormone (ACTH)-independent Cushing's syndrome (CS),which is the most frequent endocrine manifestation of Carney complex (CNC).[1] In the disease process of PPNAD,both presadrenal glands are involved and feature small brown-black nodules separated by the atrophic adrenal cortex.