硝普钠与新活素治疗难治性心衰的对比分析

New Active Element of Sodium Nitroprusside and Comparative Analysis of the Treatment of Refractory Heart Failure

目的对比分析在难治性心衰治疗中采取新活素与硝普钠治疗的临床效果。方法选取我院自2015年11月~2016年11月期间收治的124例难治性心衰患者,采取随机数字表法形式随机分为两组,为参照组(n=62)与实验组(n=62),将采取硝普钠治疗的患者作为参照组,将采取新活素治疗的患者作为实验组,分析对比经不同治疗后两组患者血清BNP、LVEF(左室射血分数)、LVEDd(左室舒张末径)以及治疗总有效率。结果实验组患者血清BNP(129.68±6.58)、治疗总有效率98.38%等显著优于参照组患者血清BNP(169.64±5.24)、治疗总有效率87.09%,数据差异有统计学意义存在(P<0.05)。但是两组患者在LVEF(左室射血分数)、LVEDd(左室舒张末径)指标方面差异无统计学意义(P>0.05)。结论将新活素治疗与硝普钠治疗应用在难治性心衰患者中均有一定效果,都可以提升生活质量以及改善患者心功能,但是新活素治疗效果更具优势。

Objective Comparison and analysis on refractory heart failure with sodium nitroprusside and new lives of two contrasting results of treatment. Methods Our hospital between November 2015 and November 2016 of the 124 cases of refractory heart failure were randomly divided into two groups, as the reference group （n= 62） and experimental group （n= 62）. Sodium nitroprusside in the treatment of patients will be taken as the reference group, will take new live treatment pa-tients as experimental group by contrast？ analysis of different treatment after two groups of patients with serum BNP LVEF （left ventricular ejection fraction ） , LVEDd（ left ventricular end diastolic diameter） and the total efficiency of treatment. Re-sults The experimental group patients serum BNP （129. 68dz6. 58） , the total efficiency of treatment 98. 38% was significantly better than the control group in serum of patients with BNP （169. 64士 5. 24. The total efficiency of treatment was 87. 0 9% , there was a significant difference between the existing data （P〈C〇 . 05）. However, there was no statistically significant differ-ence between the two groups in LVEF and LVEDd index （P〉0. 05）. Conclusion The using of new live treatment and sodium nitroprusside on patients with refractory heart failure has some effect, both can improve the quality of life and improve heart function, but the new active element has more advantages .