硒酵母联合左旋甲状腺素对淋巴细胞性甲状腺炎的治疗效果观察

The Treatment Effect of Selenium Yeast Combined with Levothyroxine on Lymphocytic Thyroiditis

目的:探究硒酵母联合左旋甲状腺素对淋巴细胞性甲状腺炎的治疗效果。方法:选取我院治疗的淋巴细胞性甲状腺炎患者64例,分为实验组和对照组,对照组患者采用左旋甲状腺素进行治疗,实验组患者在左旋甲状腺素的基础上加硒酵母进行治疗,比较两组患者的治疗效果。结果:实验组患者的治疗总有效率为93.7%,对照组患者的治疗总有效率为75.0%,两组患者的治疗总有效率比较,实验组高于对照组(P<0.05);经过治疗后,实验组患者的血促甲状腺素(TSH)、抗甲状腺球蛋白抗体(TGAb)、抗甲状腺过氧化物酶抗体(TPOAb)水平均显著低于对照组,且外周血T淋巴细胞各种亚型均高于对照组(P<0.05)。结论:硒酵母联合左旋甲状腺素治疗淋巴细胞性甲状腺炎,可以保护正常甲状腺组织,改善淋巴细胞免疫功能,提高治疗效果。

Objective To observe the therapeutic effect of selenium yeast combined with levothyroxine on lymphocytic thyroiditis.Methods： 64 casesof lymphocytic thyroiditis were selected as the research object, divided into experimental group and control group, the control group was treatedwith levothyroxine treatment, patients in the experimental group on the basis of levothyroxine plus selenium yeast treatment, compared two groupsof patients. Results： The treatment total efficiency in the experimental group was 93.7%, in the control group was 75%, the experimental group ishigher than the control group （P〈0.05）; after treatment, the patients blood thyrotropin （TSH）, thyroglobulin antibody （TGAb）, anti thyroid peroxidaseantibody （TPOAb） levels were significantly lower than the control group, and peripheral blood T lymphocyte subtypes were higher than the controlgroup （P〈0.05）. Conclusion： Selenium yeast combined with levothyroxine treatment of lymphocytic thyroiditis, can protect the normal thyroid tissue,improve the immune function of lymphocytes, and improve the therapeutic effect.