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Notch 1、Notch 2在肾脏发育及肾纤维化中的作用研究进展 被引量:4

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摘要 Notch信号通路与肾脏胚胎细胞发育、肾脏肿瘤、肾纤维化过程密切相关,信号通路的细胞内调节因子γ-分泌酶抑制剂可抑制肾纤维化过程。信号途径Notch 1、Notch 2受体均参与了肾脏的发育及肾纤维化过程,但两者在其中的作用存在着区别。本文围绕Notch 1、Notch 2在肾脏发育及肾纤维化中的作用的研究进展做一综述。
作者 冯定浩 李均
出处 《广西医学》 CAS 2017年第12期1905-1907,共3页 Guangxi Medical Journal
基金 国家自然科学基金(81660746)
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