双镜联合治疗轻型急性胆源性胰腺炎的临床疗效

Clinical efficacy of endoscopy combined with laparoscopy in treatment of mild acute biliary pancreatitis

目的探讨应用双镜(十二指肠镜及腹腔镜)联合治疗轻型急性胆源性胰腺炎的方法及临床效果。方法回顾性分析2012年6月至2016年1月收治的80例轻型急性胆源性胰腺炎患者资料,根据治疗方法分为两组:双镜治疗组(42例)和开腹手术组(38例)。采用SPSS 13.0软件进行分析,对术后腹痛缓解时间、住院时间、住院费用等指标采用均数±标准差进行描述,独立t检验进行比较;术后并发症发生率采用χ2检验比较。P<0.05差异有统计学意义。结果两组患者腹痛缓解时间差异无统计学意义(P>0.05);但在住院时间、住院费用、手术并发症发生率方面,双镜治疗组分别为(12.5±2.3)d、(16 311.9±2 382.8)元、11.9%,明显低于开腹手术组(19.6±3.2)d、(20 644.7±2 601.8)元,26.3%;差异均有统计学意义(t=-11.57、t=-7.775、χ2=5.414,P<0.05)。结论双镜联合治疗轻型急性胆源性胰腺炎,效果显著,是一种理想的微创治疗手段。

Objective To investigate the method and the clinical effect of endoscopy combined with laparoscopy in treatment of mild acute biliary pancreatitis . Methods The clinical data of 80 patients with gallstone complicated with acute biliary pancreatitis treated in our hospital from June 2012 to January 2016 were retrospectively analyzed .The patients were divided into two groups according to the treatment way：the endoscopic and laparoscopic group （n=42） and the open surgery group （n=38）.SPSS13.0 statistical analysis software was used to analysis , abdominal pain relief time , hospitalization time and hospitalization costs, such data were showed in the form of x-±s, and compared with method of t test.The postoperative complications incidence rate was compared with chi -square test.If P〈0.05, the difference was statistically significant . Results The abdominal pain relief time between the two groups were not significantly statistical different （ P 〉0.05 ）, but the hospitalization time, hospitalization costs, postoperative complications incidence rate in the endoscopic and laparoscopic group respectively （12.5 ±2.3） days, （16311.9 ±2382.8） yuan, 11.9%, were significantly lower than that in the open surgery group （19.6 ± 3.2 ） days, （ 20644.7 ±2601.8 ） yuan, 26.3%; the differences were statistically significant （t=-11.57, t=-7.775,χ2 =5.414, P〈0.05）. Conclusions The treatment of mild acute biliary pancreatitis with endoscopy combined with laparoscopy is an effective and minimally invasive method .