摘要
不同作用机制的口服降糖药(OAD)联合治疗T2DM在临床应用中已十分广泛,其中二甲双胍联合吡格列酮是中华医学会糖尿病学分会、美国糖尿病协会等国内外指南推荐的首选治疗方案之一。吡格列酮二甲双胍片作为二者的固定复方制剂,具有经济方便的优点,同时提高了患者的用药依从性。临床应用时可根据患者的具体情况单独使用吡格列酮二甲双胍片,或与其他多种OADs联合用药。为提高临床医生对此类单片复方制剂的认识,促进基层治疗的合理用药,根据现有的循证证据,制定了《吡格列酮二甲双胍复方制剂临床应用专家建议》,分别从临床地位、作用机制、疗效、安全、推荐人群和特殊人群等方面进行阐述。
It is more and more common in clinical practice to use combination therapy(first-line plus second line and or third line hypoglycemic agents)for the treatment of type 2 diabetes.Metformin combined Pioglitazone is a recommended combination by the Chinese Diabetes Society and American Diabetes Associationand other organization like International Diabetes Federation guideline in treatment of type 2 diabetes.The fixed-dose combination(FDC)of Pioglitazone and Metformin may increase patients' medication compliance.Pioglitazone and Metformin tablets can be used alone,or be combined with other hypoglycemic agents in clinical practice.In order to help clinicians to know well FDC,here we draw up this recommendation based on the evidence of efficacy,safety,indications and side effects for Pioglitazone and Metformin combination.
出处
《中国糖尿病杂志》
CAS
CSCD
北大核心
2017年第12期1057-1063,共7页
Chinese Journal of Diabetes
关键词
吡格列酮二甲双胍片
吡格列酮
二甲双胍
临床应用
专家建议
Pioglitazone and Metformin tablets
Pioglitazone
Metformim Clinical practice
Recom-mendation