脊髓损伤后大脑网络连接变化的功能MRI研究进展

The research progresses on the change of brain network functional connectivity after spinal cord injury

脊髓损伤(SCI)后大脑功能的重塑对患者的感觉运动恢复起着重要作用,但亦会导致病理性损害。到目前为止,其重塑和对功能影响的机制尚不清楚。静息态f MRI作为一种无创且能直观显示脑区活动的技术,已经成为评估大脑功能变化的重要手段,为SCI后脑网络及功能连接的机制研究提供了有效的方法。本文针对SCI后静息态脑功能连接(FC)的变化及其可能机制进行综述。

The reorganization of brain function after spinal cord injury（ SCI） plays an important role in the recovery of sensory motor activity,but also leads to pathological damage. At present,the mechanism of this reorganization is unclear. As a non-invasive technique,resting state f MRI can visually display the activity of brain regions,and has become an important methods to evaluate the changes of brain function,and it provides an effective method for the study of the mechanism of brain network and functional connectivity after SCI. In this paper,we reviewed the research progresses on the changes in the functional connectivity（ FC）and the possible mechanisms studied by resting state brain network after SCI.